NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside) are popular NAD+ precursors. Both have the ability to elevate NAD levels of nicotinamide adenine dinucleotide. When it comes to research on diseases, health, and aging, NAD has been at the forefront in recent years. There is a lot of misinformation out there regarding NMN and NR supplements. But this article will debunk the myths.
How Do They Differ?
NR has a longer history compared to NMN and is usually considered safer and more effective. Still NMN is available for sale as a dietary supplement. When the body absorbs NR, it penetrates the cells directly; while NMN doesn’t. The later must be converted into NR first before it enters the cells. Chemically, the two compounds are identical except that there is a phosphate group present in NMN which requires the supplement to be synthesized into NR so it can be absorbed at a cellular level. For this matter, no NAD+ supplement gives an advantage over the NR supplement. The fact is NMN has a bigger structure with multiple phosphates and so must be broken into smaller parts to enter the cell. And once it gets into the cell, it reforms into NAD+ again.
Reasons You Need Both NMN and NR
The big question is: does it matter how these molecules get into the cell? First and foremost, NMN and NR supplements will both benefit the body by boosting the NAD+ level which tends to decline with age. The body needs NAD+ for metabolism, energy production, and in the activation of sirtuins (proteins that control cellular health). Sure, the diet can replenish the tissues with NAD+ precursors. However, the trace amounts of NAD that naturally occur in foods may not be enough to boost NAD+ to optimal levels. So, supplementing the diet with NMN and NR helps to bridge the gap.
The Bottom Line
Your body needs NAD to carry out almost all the metabolic and redox reactions. Moreover, it helps with the repair of damaged cells and slowing down the aging process. Do you want to maintain a youthful look and a healthy body as you grow old? Then you can supplement your diet with these natural compounds. In addition, consider foods such as foods like mushrooms, dairy milk, and fish which are natural sources of NR. Fish varieties like sardines, tuna, and salmons are NAD boosters. As for the mushrooms, go for the crimini varieties. Like a fountain for youth, NAD should never lack in your diet.
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